走進(jìn)哈獸研
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1、個(gè)人簡歷
鐘功勛，男，博士，研究員，博士生導(dǎo)師，重要人獸共患病與烈性外來病創(chuàng)新團(tuán)隊(duì)，中國農(nóng)業(yè)科學(xué)院“青年英才”。一直致力于新型冠狀病毒感染、裂谷熱、流感等烈性人獸共患傳染病研究，近年來作為團(tuán)隊(duì)骨干參與新冠病毒動物易感性、動物感染模型的建立和應(yīng)用等方面的研究，并取得突破性進(jìn)展，于2021年獲科技部“全國科技系統(tǒng)抗擊新冠肺炎疫情先進(jìn)個(gè)人”表彰。以第一或通訊（含共同）作者在Science、National Science Review、Nature Communications、Protein & Cell、Emerging Infectious Diseases、Journal of Virology等雜志發(fā)表SCI論文12篇，累計(jì)影響因子182。
2、聯(lián)系方式
電話：0451-51051815
電子郵箱：zhonggongxun@caas.cn
通訊地址：哈爾濱市香坊區(qū)哈平路678號
3、教育經(jīng)歷
1999.09 – 2003.07 浙江大學(xué)動物科學(xué)專業(yè) 學(xué)士
2004.09 – 2007.07 中國農(nóng)業(yè)科學(xué)院研究生院預(yù)防獸醫(yī)專業(yè) 碩士
2007.09 – 2010.07 中國農(nóng)業(yè)科學(xué)院研究生院預(yù)防獸醫(yī)專業(yè) 博士
4、工作經(jīng)歷
2010.09 – 2019.05 美國威斯康辛大學(xué)麥迪遜分校 博士后，助理科學(xué)家
2019.06 – 至今 中國農(nóng)業(yè)科學(xué)院哈爾濱獸醫(yī)研究所重要人獸共患病與烈性外來病團(tuán)隊(duì)，研究員
5、代表性論文與著作
1. Shi J#, Wen Z#, Zhong G#, Yang H#, Wang C#, Huang B#, Liu R, He X, Shuai L, Sun Z, Zhao Y, Liu P, Liang L, Cui P, Wang J, Zhang X, Guan Y, Tan W, Wu G*, Chen H*, Bu Z*. Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS-coronavirus 2. Science 2020, 368:1016-1020.
2. Zhao M#, Zhu Y#, Zhang L#, Zhong G#, Tai L, Liu S, Yin G, Lu J, He Q, Li, M, Zhao R, Wang H, Huang W, Fan C, Shuai L, Wen Z, Wang C, He X, Chen Q, Liu B, Xiong X, Bu Z#, Wang Y*, Sun F* and Yang J*. Novel cleavage sites identified in SARS-CoV-2 spike protein reveal mechanism for cathepsin L-facilitated viral infection and treatment strategies. Cell Discov ery 2022, 8(1):53.
3. Wang J#, Shuai L#, Wang C#, Liu R#, He X, Zhang X, Sun Z, Shan D, Ge J, Wang X, Hua R, Zhong G*, Wen Z*, Bu Z*. Mouse-adapted SARS-CoV-2 replicates efficiently in the upper and lower respiratory tract of BALB/c and C57BL/6J mice. Protein Cell 2020, 11(10):776-782.
4. Wu S#, Zhong G#, Zhang J#, Shuai L#, Zhang Z, Wen Z, Wang B, Zhao Z, Song X, Chen Y, Liu R, Fu L, Zhang J, Guo Q, Wang C, Yang Y, Fang T, Lv P, Wang J, Xu J, Li J, Yu C, Hou L*, Bu Z*, Chen W*. A single dose of an adenovirus-vectored vaccine provides protection against SARS-CoV-2 challenge. Nature Communications 2020, 11:4081.
5. Shuai L#, Zhong G#, Yuan Q#, Wen Z#, Wang C#, He X#, Liu R, Wang J, Zhao Q, Liu Y, Huo N, Deng J, Bai J, Wu H, Guan Y, Shi J, Tian K, Xia N, Chen H*, Bu Z*. Replication, pathogenicity, and transmission of SARS-CoV-2 in minks. National Science Review 2021, 8(3):nwaa291.
6. Zhong G, Fan S, Hatta M, Nakatsu S, Walters KB, Lopes TJS, Wang JIH, Ozawa M, Karasin A, Li Y, Tong SX, Donis RO, Neumann G*, Kawaoka Y*. Mutations in the Neuraminidase-Like Protein of Bat Influenza H18N11 Virus Enhance Virus Replication in Mammalian Cells, Mice, and Ferrets. J Virol 2020, 94:e01416-19.
7. Zhong G#, Fan S#, Lopes TJS, Le MQ, van Bakel H, Dutta J, Smith GJD, Jayakumar J, Nguyen HLK, Hoang PVM, Halfmann P, Hatta M, Su YCF, Neumann G*, Kawaoka Y*. Isolation of Highly Pathogenic H5N1 Influenza Viruses in 2009-2013 in Vietnam. Front Microbiol 2019, 10:1411.
8. Watanabe T#, Zhong G#, Russell CA#, Nakajima N, Hatta M, Hanson A, McBride R, Burke DF, Takahashi K, Fukuyama S, Tomita Y, Maher EA, Watanabe S, Imai M, Neumann G, Hasegawa H, Paulson JC, Smith DJ, Kawaoka Y*. Circulating avian influenza viruses closely related to the 1918 virus have pandemic potential. Cell Host Microbe 2014, 15(6):692-705.
9. Zhong G, Le MQ, Lopes T, Halfmann P, Hatta M, Fan S, Neumann G*, and Kawaoka Y*. Mutations in the PA Protein of Avian H5N1 Influenza Viruses Affect Polymerase Activity and Mouse Virulence. J Virol 2018, 92(4): e01557-17.
10. Hatta M#, Zhong G#, Gao Y#, Nakajima N#, Fan S#, Chiba S, Deering K, Ito M, Imai M, Kiso M, Nakatsu S, Lopes T, Thompson A, McBride R, Suarez D, Macken C, Sugita S, Neumann G, Hasegawa H, Paulson J, Toohey-Kurth K, and Kawaoka Y*. Characterization of a Feline Influenza A(H7N2) Virus. Emerg Infect Dis 2018, 24(1),75-86.
11. Li Y#, Shi J#, Zhong G#, Deng G#, Tian G, Ge J, Zeng X, Song J, Zhao D, Liu L, Jiang Y, Guan Y, Bu Z, Chen H*. Continued evolution of H5N1 influenza viruses in wild birds, domestic poultry and humans in China from 2004 to 2009. J Virol 2010, 84(17):8389-97.
12. Tang Y#, Zhong G#, Zhu L#, Liu X, Shan Y, Feng H, Bu Z, Chen H*, and Wang C*. Herc5 attenuates influenza A virus by catalyzing ISGylation of viral NS1 protein. J Immunol 2010, 184(10):5777-90.
6、獲得獎(jiǎng)勵(lì)
2021年獲科技部“全國科技系統(tǒng)抗擊新冠肺炎疫情先進(jìn)個(gè)人”表彰。
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