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1、個(gè)人簡歷
賈洪林，男，博士，研究員，博士研究生導(dǎo)師，寵物疫病創(chuàng)新團(tuán)隊(duì)首席。目前承擔(dān)國家重點(diǎn)研發(fā)專項(xiàng)，國家自然科學(xué)基金以及省自然科學(xué)基金等多個(gè)項(xiàng)目。主要研究方向?yàn)樨垖櫸镆卟〉葘櫸镌慈双F共患病的病原生物學(xué)研究以及防控制劑研發(fā)。在PLoS Pathogens、Autophagy、Nature Structural & Molecular Biology、mBio和JV等國際著名期刊發(fā)表SCI文章50多篇，被引用700多次，擔(dān)任多個(gè)國際期刊審稿人。
2、聯(lián)系方式
研究方向：寵物傳染病研究
電話：045151051782
郵箱：jiahonglin@caas.cn
通訊地址：哈爾濱市哈平路678號
3、工作經(jīng)歷
2004.07-2005.01 延邊大學(xué) 助教
2005.02-2006.03 日本帶廣畜產(chǎn)大學(xué)國立原蟲病研究中心 研究職員
2009.04-2011.09 日本北海道大學(xué)人獸共患病研究中心 博士后
2011.10-2020.12 中國農(nóng)業(yè)科學(xué)院哈爾濱獸醫(yī)研究所 副研究員
2021.01-至今 中國農(nóng)業(yè)科學(xué)院哈爾濱獸醫(yī)研究所 研究員
4、承擔(dān)項(xiàng)目
(1) “十四五” 國家重點(diǎn)研發(fā)計(jì)劃項(xiàng)目，2023-2026
(2) 黑龍江省杰出青年基金項(xiàng)目，2022-2025
(3) 黑龍江省重點(diǎn)研發(fā)計(jì)劃項(xiàng)目，2022-2025
(4) “十四五” 國家重點(diǎn)研發(fā)計(jì)劃項(xiàng)目子課題，2022-2025
(5) 國家自然科學(xué)基金面上項(xiàng)目，2018-2022
(6) “十三五” 國家重點(diǎn)研發(fā)計(jì)劃項(xiàng)目子課題，2017-2022
(7) “十三五” 國家重點(diǎn)研發(fā)計(jì)劃項(xiàng)目子課題，2017-2022
(8) 國家自然科學(xué)基金青年基金項(xiàng)目，2012-2015
(9) 黑龍江省自然科學(xué)基金面上項(xiàng)目，2015-2017
5、代表論文與著作
1. Heng W, Zang D, Li R, Jiang Q, Liu J, Jia H, Kang H. A novel replication-deficient FCV vaccine provides strong immune protection in cats. J Virol. 2025 Jul 8:e0009325. 共同通訊
2. Cao H, Gu H, Kang H, Jia H. Development of a rapid reverse genetics system for feline coronavirus based on TAR cloning in yeast. Front Microbiol. 2023, 14:1141101. 通訊作者
3. Fu J, Zhao L, Chen H, Cao S, Jia H*. An unconventional SNARE complex mediates exocytosis at the plasma membrane and vesicular fusion at the apical annuli in Toxoplasma gondii. PLoS Pathogens. 2023, 19(3):e1011288. 通訊作者
4. Cao H, Gu H, Kang H* and Jia H*. Development of a rapid reverse genetics system for feline coronavirus based on TAR cloning in yeast. Front. Microbiol. 2023, 14:1141101.
5. Fu J, Zhao L, Pang Y, Chen H, Yamamoto H, Chen Y, Li Z, Mizushima N, Jia H*. Apicoplast biogenesis mediated by ATG8 requires the ATG12-ATG5-ATG16L and SNAP29 complexes in Toxoplasma gondii. Autophagy. 2023, 19(4):1258-1276. 通訊作者
6. The Dissection of SNAREs Reveals Key Factors for Vesicular Trafficking to the Endosome-like Compartment and Apicoplast via the Secretory System in Toxoplasma gondii. Cao S., Yang J., Fu J., Chen H., Jia H*. mBio. 2021,12(4):e0138021. 通訊作者
7. Evolution from covalent conjugation to non-covalent interaction in the ubiquitin-like ATG12 system. Pang, Y., Yamamoto, H., Sakamoto, H., Oku, M., Mutungi, J. K., Sahani, M. H., Kurikawa, Y., Kita, K., Noda, N. N. & Sakai, Y., Jia, H.*, Mizushima, N*. Nature structural & molecular biology, 2019, 26: 289-296. 共同通訊作者
8. TgMAP1c is involved in apicoplast biogenesis in Toxoplasma gondii. Zheng, J., Su, W., Cao, S., Zhang, Z., Du, C., Jia, H.* International Journal for Parasitology, 2020,50 :487-499. 通訊作者
9. Hydroxylamine and Carboxymethoxylamine Can Inhibit Toxoplasma gondii Growth through an Aspartate Aminotransferase-Independent Pathway, Li, J., Guo, H., Galon, E.M., Gao, Y., Lee, S., Liu, M., Li, Y., Ji, S., Jia, H*., Xuan，X*., Antimicrob Agents Chemother, 2020, 64(3): e01889-19. 共同通訊作者
10. GABARAPL2 Is Critical for Growth Restriction of Toxoplasma gondii in HeLa Cells Treated with Gamma Interferon. Zhang, Z., Gu, H., Li, Q., Zheng, J., Cao, S., Weng, C., Jia, H.* Infection and Immunity, 2020, 88: e00054-20. 通訊作者
11. The Sec1/Munc18‐like proteins TgSec1 and TgVps45 play pivotal roles in assembly of the pellicle and sub‐pellicle network in Toxoplasma gondii. Cao, S., Chen, H., Liang, X., Fu, J., Wang, S., Zheng, J., Zhang, Z., Pang, Y., Wang, J. & Shen, B., Jia, H.*. Molecular microbiology, 2019, 113: 208-221. 通訊作者
12. Translationally controlled tumor protein is required for the fast growth of Toxoplasma gondii and maintenance of its intracellular development. Zheng, J., Chen, Y., Li, Z., Cao, S., Zhang, Z. & Jia, H.* FASEB J, 2018, 32: 906-919. 通訊作者
13. Knockout of leucine aminopeptidase in Toxoplasma gondii using CRISPR/Cas9. Zheng, J., Jia, H.*, & Zheng, Y. International Journal for Parasitology, 2015, 45:141-148. 通訊作者
14. Characterization of aspartyl aminopeptidase from Toxoplasma gondii. Zheng, J., Cheng, Z., Jia, H.* & Zheng, Y. Sci Rep, 2016, 6: 34448. 通訊作者
15. Toxoplasma gondii Clp family protein: TgClpB1 plays a crucial role in thermotolerance. Cao, S., Nali Du, Chen, H., Pang, Yu., Zhang, Z., Zheng, J. Jia, H.* Oncotarget. 2017, 8:86117-86129.
16. Wang, M., Cao, S., Du, N., Fu, J., Li, Z., Jia, H.＊, Mingxin Song*. The moving junction protein RON4, although not critical, facilitates host cell invasion and stabilizes MJ members. Parasitology. 2017, 144(11): 1490-1497. 共同通訊
17. Functional characterization of X-prolyl aminopeptidase from Toxoplasma gondii. Yang, M., Zheng, J., Jia, H.,*, Song, M.* Parasitology. 2016, 143(11):1443-9. 共同通訊
18. Meng, X., , Zheng, J., He, X., Jia, H. *, Zhang, Y.* First characterization in China of Encephalitozoon cuniculi in the blue fox (Alopex lagopus). J Eukaryot Microbiol. 2014, 61(6):580-5.
19. Meng, X., Zheng, J., Gao, Y., Zhang, Y*. & Jia, H* . Evaluation of spore wall protein 1 as an alternative antigen for the diagnosis of Encephalitozoon cuniculi infection of farmed foxes using an enzyme-linked immunosorbent assay. Veterinary Parasitology, 2014, 203: 331-334. 通訊作者
20. Jia, H., Nishikawa, Y., Luo, Y., Yamagishi, J., Sugimoto, C., Xuan, X., Characterization of a leucine aminopeptidase from Toxoplasma gondii. Mol Biochem Parasitol 170, 1-6.
21. Jia, H., Zhou, J., Ikadai, H., Matsuu, A., Suzuki, H., Igarashi, I., Fujisaki, K., Xuan, X., 2006. Identification of a novel gene encoding a secreted antigen 1 of Babesia gibsoni and evaluation of its use in serodiagnosis. Am J Trop Med Hyg 75, 843-850.
22. Jia, H., Liao, M., Lee, E., Nishikawa, Y., Inokuma, H., Ikadai, H., Matsuu, A., Igarashi, I., Xuan, X., 2007. Development of an immunochromatographic test with recombinant BgSA1 for the diagnosis of Babesia gibsoni infection in dogs. Parasitol Res 100, 1381-1384.
23. Jia, H., Terkawi, M.A., Aboge, G.O., Goo, Y.K., Zhou, J., Lee, E.G., Nishikawa, Y., Igarashi, I., Fujisaki, K., Xuan, X., 2008. Babesia gibsoni: identification of an immunodominant, interspersed repeat antigen. Exp Parasitol 118, 146-149.
24. Jia, H., Aboge, G.O., Terkawi, M.A., Goo, Y.K., Nishikawa, Y., Kuriki, K., Lee, K.K., Jang, H.K., Kim, S., Fujisaki, K., Xuan, X., 2009. Genetic diversity of two selected antigen loci in Babesia gibsoni Asian genotype obtained from Japan and Jeju island of South Korea. Vet Parasitol 162, 142-146.
25. Jia, H., Terkawi, M.A., Aboge, G.O., Goo, Y.K., Luo, Y., Li, Y., Yamagishi, J., Nishikawa, Y., Igarashi, I., Sugimoto, C., Fujisaki, K., Xuan, X., 2009. Characterization of a leucine aminopeptidase of Babesia gibsoni. Parasitology 136, 945-952.
26. Jia, H., Terkawi, M.A., Aboge, G.O., Goo, Y.K., Ma, L., Zhou, J., Nishikawa, Y., Igarashi, I., Fujisaki, K., Xuan, X., 2009. Identification of secreted antigen 3 from Babesia gibsoni. Clin Vaccine Immunol 16, 944-948.
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