走進(jìn)哈獸研
綜合新聞
科研進(jìn)展
科研成果
人才招聘
辦公系統(tǒng)
掃一掃 關(guān)注我
1、個(gè)人簡(jiǎn)介
李婷婷，博士，中國(guó)農(nóng)業(yè)科學(xué)院哈爾濱獸醫(yī)研究所助理研究員?，F(xiàn)就職于中國(guó)農(nóng)業(yè)科學(xué)院哈爾濱獸醫(yī)研究所，進(jìn)行博士后研究工作，主要從事非洲豬瘟病毒感染與致病機(jī)制研究。主持國(guó)家自然科學(xué)基金青年基金項(xiàng)目、國(guó)家重點(diǎn)研發(fā)計(jì)劃子課題等項(xiàng)目。在Journal of Biological Chemistry（2篇），Viruses（1篇），Virology（1篇） 等雜志發(fā)表第一作者（含共同）科技論文4篇。
2、聯(lián)系方式
電話：0451-51051759
郵箱：litingting02@caas.cn; sunshine8302021@163.com
通訊地址：黑龍江省哈爾濱市香坊區(qū)哈平路678號(hào)
3、教育背景
2018.09-2021.12 中國(guó)農(nóng)業(yè)科學(xué)院 預(yù)防獸醫(yī)學(xué) 博士
2014.09-2017.06 東北林業(yè)大學(xué) 特種經(jīng)濟(jì)動(dòng)物飼養(yǎng) 碩士
2006.09-2010.06 東北林業(yè)大學(xué) 動(dòng)物科學(xué) 本科
4、工作經(jīng)歷
2011.01-2014.01 伊春林業(yè)科學(xué)院 動(dòng)物研究室 科員
2022.01-今 中國(guó)農(nóng)業(yè)科學(xué)院哈爾濱獸醫(yī)研究所 基礎(chǔ)免疫創(chuàng)新團(tuán)隊(duì) 助理研究員
5、主要科研項(xiàng)目
1. 國(guó)家自然科學(xué)基金青年基金項(xiàng)目：非洲豬瘟病毒pS273R通過(guò)切割G3BP1調(diào)控宿主應(yīng)激顆粒形成的機(jī)制（32302893，2024.01-2026.12）30萬(wàn)，主持；
2. 十四五國(guó)家重點(diǎn)研發(fā)計(jì)劃“非洲豬瘟病毒的病原生物學(xué)與致病機(jī)制”項(xiàng)目子課題：ASFV受體識(shí)別與入侵宿主細(xì)胞的分子機(jī)制（2021YFD1800102-2）180萬(wàn)，主持；
3. 國(guó)家自然科學(xué)基金聯(lián)合基金項(xiàng)目：非洲豬瘟病毒免疫調(diào)節(jié)基因的功能及其在病毒感染致病中的作用（U21A20256, 2022-01- 2025-12）260萬(wàn)，參與；
4. 國(guó)家自然科學(xué)基金專(zhuān)項(xiàng)項(xiàng)目：非洲豬瘟病毒感染與致病機(jī)制（31941002，2019.07-2022.06）300萬(wàn)，參與。
6、代表性文章
1. Tingting Li*, Jun Zheng*, Tao Huang, Xiao Wang, Jiangnan Li, Feng Jin, Wenjuan Wei, Xin Chen, Chuanxia Liu, Miaofei Bao, Gaihong Zhao, Li Huang, Dongming Zhao, Jianxin Chen, Zhigao Bu, Changjiang Weng, African swine fever virus replication inhibitors by screening of a library of FDA-approved drugs. Virology. 2024 Feb 14;593:110014.
2. Tingting Li*, Xuewen Li*, Xiao Wang, Xin Chen, Gaihong Zhao, Chuanxia Liu, Miaofei Bao, Jie Song, Jiangnan Li, Li Huang, Jun Rong, Kegong Tian, Junhua Deng, Jianzhong Zhu, Xuehui Cai, Zhigao Bu, Jun Zheng, Changjiang Weng, African swine fever virus pS273R antagonizes stress granule formation by cleaving the nucleating protein G3BP1 to facilitate viral replication. Journal of Biological chemistry, 2023 Jul;299(7):104844.
3. Xin Chen, Jun Zheng, Chuanxia Liu, Tingting Li, Xiao Wang, Xuewen Li, Miaofei Bao, Jiangnan Li, Li Huang, Zhaoxia Zhang, Zhigao Bu, Changjiang Weng, CD1d facilitates African swine fever virus entry into the host cells via clathrin-mediated endocytosis. Emerg Microbes Infect. 2023 Dec;12(2):2220575.
4. Xin Chen, Jun Zheng, Tingting Li, Chuanxia Liu, Miaofei Bao, Xiao Wang, Xuewen Li, Jiangnan Li, Li Huang, Zhaoxia Zhang, Changjiang Weng, Coreceptor AXL Facilitates African Swine Fever Virus Entry via Apoptotic Mimicry. Journal of Virology. 2023 Jul 27;97(7):e0061623.
5. Jiangnan Li, Jie Song, Shijun Zhou, Shuai Li, Jia Liu, Tingting Li, Zhaoxia Zhang, Xianfeng Zhang, Xijun He, Weiye Chen, Jun Zheng, Dongming Zhao, Zhigao Bu, Li Huang, Changjiang Weng, Development of a new effective African swine fever virus vaccine candidate by deletion of the H240R and MGF505-7R genes results in protective immunity against the Eurasia strain. Journal of Virology. 2023 Oct 31;97(10):e0070423.
6. Tingting Li*, Gaihong Zhao*, Taoqing Zhang, Zhaoxia Zhang, Xin Chen, Jie Song, Xiao Wang, Jiangnan Li, Li Huang, Lili Wen, Changyao Li, Dongming Zhao, Xijun He, Zhigao Bu, Jun Zheng, Changjiang Weng, African Swine Fever Virus pE199L Induces Mitochondrial-Dependent Apoptosis, Viruses, 2021, 13(11): 2240.
7. Gaihong Zhao*; Tingting Li* ; Xuemin Liu; Taoqing Zhang; Zhaoxia Zhang; Li Kang; Jie Song; Shijun Zhou; Xin Chen; Xiao Wang; Jiangnan Li; Li Huang; Changyao Li; Zhigao Bu; Jun Zheng; Changjiang Weng ; African swine fever virus cysteine protease pS273R inhibits pyroptosis by noncanonically cleaving gasdermin D, Journal of Biological chemistry, 2021, 298(1):101480.
掃一掃 關(guān)注我
網(wǎng)站首頁(yè)
聯(lián)系我們