走進(jìn)哈獸研
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1、個人簡歷
李明蔚，女，博士/助理研究員，豬消化道傳染病創(chuàng)新團(tuán)隊(duì)在站博士后。主要從事豬腸道冠狀病毒致病機(jī)制的研究。近年在PLoSPathogens、 Journal of Virology和Frontiers in veterinary science等雜志共發(fā)表9篇。
2、聯(lián)系方式
研究方向：獸醫(yī)微生物及其分子生物學(xué)
電話：0451-51051881
郵箱：limingwei101825@163.com
通訊地址：黑龍江省哈爾濱市南崗區(qū)哈平路678號
3、教育經(jīng)歷
2012.09-2017.06 西北農(nóng)林科技大學(xué) 動物醫(yī)學(xué)專業(yè) 學(xué)士
2017.09-2020.06 中國農(nóng)業(yè)科學(xué)院哈爾濱獸醫(yī)研究所 預(yù)防獸醫(yī) 碩士
2020.09-2023.6 中國農(nóng)業(yè)科學(xué)院哈爾濱獸醫(yī)研究所 預(yù)防獸醫(yī) 博士
4、工作經(jīng)歷
2023.08-至今 中國農(nóng)業(yè)科學(xué)院哈爾濱獸醫(yī)研究所 助理研究員
5、代表性論文與著作
1. Li, M., Y. Wu, J. Chen, H. Shi, Z. Ji, X. Zhang, D. Shi, J. Liu, J. Tian, X. Wang, Z. Shi, H. Zhang, H. Zhang, L. Guo and L. Feng (2022). "Innate Immune Evasion of Porcine Epidemic Diarrhea Virus through Degradation of the FBXW7 Protein via the Ubiquitin-Proteasome Pathway." J Virol 96(5): e0088921.
2. Wu, Y., M. Li, J. Tian, H. Yan, Y. Pan, H. Shi, D. Shi, J. Chen, L. Guo and L. Feng (2023). "Broad antagonism of coronaviruses nsp5 to evade the host antiviral responses by cleaving POLDIP3." PLoS Pathog 19(10): e1011702.
3. Li, M., L. Guo and L. Feng (2022). "Interplay between swine enteric coronaviruses and host innate immune." Front Vet Sci 9: 1083605.
4. Wu, Y., Y. Wang, X. Wang, M. Li, H. Yan, H. Shi, D. Shi, J. Chen, L. Guo and L. Feng (2024). "Elevation of IL-8 secretion induced by PEDV infection via NF-κB signaling pathway." Front Cell Infect Microbiol 14: 1422560.
5. Wu, Y., Z. Shi, J. Chen, H. Zhang, M. Li, Y. Zhao, H. Shi, D. Shi, L. Guo and L. Feng (2022). "Porcine deltacoronavirus E protein induces interleukin-8 production via NF-κB and AP-1 activation." Vet Microbiol 274: 109553.
6. Ji, Z., D. Shi, H. Shi, X. Wang, J. Chen, J. Liu, D. Ye, Z. Jing, Q. Liu, Q. Fan, M. Li, G. Cong, J. Zhang, Y. Han, X. Zhang and L. Feng (2021). "A porcine epidemic diarrhea virus strain with distinct characteristics of four amino acid insertion in the COE region of spike protein." Vet Microbiol 253: 108955.
7. Wu, Y., H. Zhang, J. Chen, Z. Shi, M. Li, Y. Zhao, H. Shi, D. Shi, L. Guo and L. Feng (2022). "Stromal Antigen 2 Deficiency Induces Interferon Responses and Restricts Porcine Deltacoronavirus Infection." Viruses 14(8).
8. Wu, Y., H. Zhang, Z. Shi, J. Chen, M. Li, H. Shi, D. Shi, L. Guo and L. Feng (2020). "Porcine Epidemic Diarrhea Virus nsp15 Antagonizes Interferon Signaling by RNA Degradation of TBK1 and IRF3." Viruses 12(6).
9. Ye, D., Z. Ji, H. Shi, J. Chen, D. Shi, L. Cao, J. Liu, M. Li, H. Dong, Z. Jing, X. Wang, Q. Liu, Q. Fan, G. Cong, J. Zhang, Y. Han, J. Zhou, J. Gu, X. Zhang and L. Feng (2020). "Molecular characterization of an emerging reassortant mammalian orthoreovirus in China." Arch Virol 165(10): 2367-2372.
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