掃一掃 關(guān)注我

孫元,男,博士,研究員,博士生導(dǎo)師,青年龍江學(xué)者,黑龍江省杰出青年基金和中國農(nóng)業(yè)科學(xué)院—大北農(nóng)人才獎(jiǎng)獲得者。中國農(nóng)業(yè)科學(xué)院哈爾濱獸醫(yī)研究所豬烈性傳染病創(chuàng)新團(tuán)隊(duì)助理首席、黨支部書記。哈爾濱維科生物技術(shù)有限公司總經(jīng)理。
主持十四五國家重點(diǎn)研發(fā)計(jì)劃項(xiàng)目課題1項(xiàng),十三五國家重點(diǎn)研發(fā)計(jì)劃項(xiàng)目子課題2項(xiàng);國家自然科學(xué)基金面上項(xiàng)目3項(xiàng),青年項(xiàng)目1項(xiàng);哈爾濱市科技創(chuàng)新人才專項(xiàng)資金項(xiàng)目1項(xiàng)。獲國家發(fā)明專利11項(xiàng),獲轉(zhuǎn)基因微生物安全證書2項(xiàng),臨床試驗(yàn)批件1項(xiàng)。獲黑龍江省科學(xué)技術(shù)創(chuàng)新獎(jiǎng)等3項(xiàng)。以第一/共第一作者或通訊/共通訊作者發(fā)表SCI文章30余篇。作為第一完成人,首創(chuàng)了腺病毒/甲病毒復(fù)制子嵌合載體豬瘟標(biāo)記疫苗,該疫苗已完成臨床試驗(yàn),正進(jìn)行新獸藥注冊,已完成轉(zhuǎn)化。此外,作為第一完成人構(gòu)建了一系列預(yù)防豬瘟等重要傳染病的活載體疫苗以及偽狂犬病病毒變異株基因缺失疫苗。另外,在偽狂犬病病毒神經(jīng)傳導(dǎo)、體內(nèi)示蹤和潛伏感染以及非洲豬瘟病毒基因功能和疫苗研究等方面進(jìn)行了深入的研究。
一、聯(lián)系方式
研究方向:動(dòng)物疫苗與分子免疫學(xué)
電話:13945100699
郵箱:sunyuan@caas.cn
通訊地址:黑龍江省哈爾濱市香坊區(qū)哈平路678號
二、教育經(jīng)歷
1998.09 - 2003.06 東北農(nóng)業(yè)大學(xué) 動(dòng)物醫(yī)學(xué) 學(xué)士學(xué)位
2003.09 - 2006.06 中國農(nóng)業(yè)科學(xué)院蘭州獸醫(yī)研究所 預(yù)防獸醫(yī)學(xué) 碩士學(xué)位
2009.09 - 2012.06 中國農(nóng)業(yè)科學(xué)院哈爾濱獸醫(yī)研究所 預(yù)防獸醫(yī)學(xué) 博士學(xué)位
三、工作經(jīng)歷
2006.07 - 2009.11 中國農(nóng)業(yè)科學(xué)院哈爾濱獸醫(yī)研究所 研究實(shí)習(xí)員
2009.12 - 2013.11 中國農(nóng)業(yè)科學(xué)院哈爾濱獸醫(yī)研究所 助理研究員
2013.12 - 2018.12 中國農(nóng)業(yè)科學(xué)院哈爾濱獸醫(yī)研究所 副研究員
2019.01 – 至今 中國農(nóng)業(yè)科學(xué)院哈爾濱獸醫(yī)研究所 研究員
四、主持項(xiàng)目
1. 十四五國家重點(diǎn)研發(fā)計(jì)劃課題:微生態(tài)/細(xì)菌載體非洲豬瘟重組疫苗研究(2021YFD1801403,2021.12-2024.12),1000萬元;
2. 國家自然科學(xué)基金面上項(xiàng)目:非洲豬瘟病毒毒力相關(guān)新基因的鑒定及其調(diào)控病毒毒力的機(jī)制(32072854,2021.01-2024.12),58萬元;
3. 國家自然科學(xué)基金面上項(xiàng)目:偽狂犬病病毒變異株和經(jīng)典株在神經(jīng)軸突中逆向傳導(dǎo)差異的分子機(jī)制(31870152,2019.01-2022.12),59萬元;
4. 國家自然科學(xué)基金面上項(xiàng)目:偽狂犬病病毒變異株神經(jīng)毒力增強(qiáng)的分子機(jī)制(31570149,2016.01-2020.12),77萬元;
5. 十三五國家重點(diǎn)研發(fā)計(jì)劃項(xiàng)目子課題:偽狂犬病病毒經(jīng)典株、變異株毒力基因的鑒定及致病力差異的分子基礎(chǔ)(2016YFD0500100,2016.07-2020.12),115萬元;
6. 黑龍江省杰出青年基金:偽狂犬病病毒UL54蛋白調(diào)控其潛伏感染再激活的分子機(jī)制(JQ2022C007,2022.07-2025.07),50萬元;
7. 國家自然科學(xué)基金青年基金項(xiàng)目:偽狂犬病病毒/日本腦炎病毒復(fù)制子嵌合疫苗載體的構(gòu)建及評價(jià)(31200690,2013.01-2015.12),25萬元;
8. 2014年哈爾濱市科技創(chuàng)新人才專項(xiàng)資金項(xiàng)目-青年后備人才計(jì)劃:偽狂犬病病毒變異株載體豬瘟疫苗的研制(2014RFQYJ126,2014.06-2016.06),4萬元。
五、代表論文
1. Liu D, Li LF, Zhai H, Wang T, Lan J, Cao M, Yao M, Wang Y, Li J, Song X, Sun Y*, Qiu HJ*. Resveratrol inhibits African swine fever virus replication by exerting antiviral and antioxidative stress activities via the Nrf2 signaling pathway. Emerg Microbes Infect. 2025 Feb 18:2469662. (IF=8.4)
2. Zhong D, Lu Z, Xia Y, Wu H, Zhang X, Li M, Song X, Wang Y, Moon A, Qiu HJ*, Li Y*, Sun Y*. Ferritin nanoparticle delivery of the E2 protein of classical swine fever virus completely protects pigs from lethal challenge. Vaccines (Basel). 2024 Jun 5;12(6):629. (IF=5.2)
3. Lan J, Luo R, Liu D, Qi C, Song X, Lu Z, Huang R, Yang Y, Sun Y*, Zhang Y*, Wang T*, Qiu HJ*. A novel high-throughput screen identifies phenazine-1-carboxylic acid as an inhibitor of African swine fever virus replication in primary porcine alveolar macrophages. Vet Res. 2025 Feb 8;56(1):37. (IF=3.7)
4. Zhang X, Wu H, Gao T, Li Y, Zhong D, Li M, Li S, Ma C, Moon A, Fu Q*, Qiu HJ*, Sun Y*. A recombinant pseudorabies virus surface - displaying the classical swine fever E2 protein induces specific antibodies rapidly. Vet Microbiol. 2024 Nov;298:110240. (IF=2.4)
5. Guan X, Wang T, Gao Y, Zhai H, Jiang F, Hou Q, Yang X, Wu H, Li L-F, Luo Y, Li S, Sun Y*, Qiu HJ*, Li Y*. The CP123L protein of African swine fever virus is a membrane-associated, palmitoylated protein required for viral replication. J Virol. 2025 Jan 31;99(1):e0144524. (IF=4.0)
6. Li M, Liu X, Peng D, Yao M, Wang T, Wang Y, Cao H, Wang Y, Dai J, Luo R, Deng H, Li J, Luo Y, Li Y, Sun Y*, Li S*, Qiu HJ*, Li LF*. The I7L protein of African swine fever virus is involved in viral pathogenicity by antagonizing the IFN-γ-triggered JAK-STAT signaling pathway through inhibiting the phosphorylation of STAT1. PLoS Pathog. 2024 Sep 26;20(9):e1012576. (IF=5.5)
7. Yang X, Sun E, Zhai H, Wang T, Wang S, Gao Y, Hou Q, Guan X, Li S, Li LF, Wu H, Luo Y, Li S, Sun Y*, Zhao D*, Li Y*, Qiu HJ*. The antibodies against the A137R protein drive antibody-dependent enhancement of African swine fever virus infection in porcine alveolar macrophages. Emerg Microbes Infect. 2024 Dec;13(1):2377599. (IF=8.4)
8. Wang Y, Ma C, Wang S, Wu H, Chen X, Ma J, Wang L*, Qiu HJ*, Sun Y*. Advances in the immunoescape mechanisms exploited by alphaherpesviruses. Front Microbiol. 2024 Jun 19;15:1392814. (IF=4.0)
9. Lu Z, Luo R, Lan J, Chen S, Qiu HJ*, Wang T*, Sun Y*. The MGF300-2R protein of African swine fever virus promotes IKKβ ubiquitination by recruiting the E3 ubiquitin ligase TRIM21. Viruses. 2024 Jun 12;16(6):949. (IF=3.8)
10. Chen S, Wang T, Luo R, Lu Z, Lan J, Sun Y*, Fu Q*, Qiu HJ*. Genetic variations of African swine fever virus: major challenges and prospects. Viruses. 2024 Jun 4;16(6):913. (IF=3.8)
11. Song X, Li Y, Wu H, Qiu H, Sun Y. T-cell epitope-based vaccines: A promising strategy for prevention of infectious diseases. Vaccines (Basel). 2024 Oct 17;12(10):1181. (IF=5.2)
12. Wang T, Luo R, Zhang J, Lu Z, Li LF, Zheng YH, Pan L, Lan J, Zhai H, Huang S, Sun Y*, Qiu HJ*. The MGF300-2R protein of African swine fever virus is associated with viral pathogenicity by promoting the autophagic degradation of IKKα and IKKβ through the recruitment of TOLLIP. PLoS Pathog. 2023; 11;19(8):e1011580. (IF=6.7)
13. Wang T, Luo R, Zhang J, Lan J, Lu Z, Zhai H, Li LF, Sun Y*, Qiu HJ*. The African swine fever virus MGF300-4L protein is associated with viral pathogenicity by promoting the autophagic degradation of IKKβ and increasing the stability of IκBα. Emerg Microbes Infect. 2024; 13(1):2333381. (IF=13.2)
14. Wu H, Qi H, Wang B, Li M, Qu L, Li S, Luo Y, Li LF, Zheng GL, Qiu HJ*, Sun Y*. The mutations on the envelope glycoprotein D contribute to the enhanced neurotropism of the pseudorabies virus variant. J Biol Chem. 2023; 299(11):105347. (IF=4.8)
15. Liu D, Pan L, Zhai H, Qiu HJ*, Sun Y*. Virus tracking technologies and their applications in viral life cycle: research advances and future perspectives. Front Immunol. 2023; 14:1204730. (IF=7.3)
16. Pan L1, Li M1, Zhang X, Xia Y, Mian AM, Wu H*, Sun Y*, Qiu HJ*. Establishment of an in vitro model of pseudorabies virus latency and reactivation and identification of key viral latency-associated genes. Viruses. 2023; 15(3):808. (IF=5.048)
17. Bing Wang?, Hongxia Wu?, Hansong Qi?, Hanglin Li, Li Pan, Lianfeng Li, Kehui Zhang, Mengqi Yuan, Yimin Wang*, Hua-Ji Qiu*, Yuan Sun*. Histamine is responsible for the neuropathic itch induced by the pseudorabies virus variant in a mouse model. Viruses. 2022 May 17; 14:1067. (IF=5.048)
18. Maowen Sun?, Shaoxiong Yu?, Hailiang Ge?, Tao Wang, Yongfeng Li, Pingping Zhou, Li Pan, Yu Han, Yuying Yang, Yuan Sun*, Su Li*, Lian-feng Li*, Hua-Ji Qiu*. The A137R protein of African swine fever virus inhibits type I interferon production via the autophagy-mediated lysosomal degradation of TBK1. J Virol 2022 May 11;96(9): e0195721. (IF=5.103)
19. Mengnan Qi1a, Li Pan1a, Ying Gaoa, Miao Lia, Yanjin Wanga, Lian-Feng Lia, Chen Jib, Yuan Suna*, Hua-Ji Qiua*. Synergistic inactivation of African swine fever virus by a highly complexed iodine combined with compound organic acids. Appl Environ Microbiol. 2022 May 19:e0045222. (IF=4.792)
20. Zhou P#, Li LF#, Zhang K#, Wang B, Tang L, Li M, Wang T, Sun Y*, Li S*, Qiu HJ*. Deletion of the H240R gene of African swine fever virus decreases Infectious progeny virus production due to aberrant virion morphogenesis and enhances the inflammatory cytokine expression in porcine Macrophages. J Virol. 2022 Apr 13;96(7):e0030822. (IF=5.103)
21. Yue C#, Xiang W#, Huang X#, Sun Y#, Xiao J, Liu K, Sun Z, Qiao P, Li H, Gan J, Ba L, Chai Y, Qi J, Liu P, Qi P, Zhao Y, Li Y, Qiu HJ*, Gao GF*, Gao G*, Liu WJ*. Mooring stone-like Arg114 pulls diverse bulged peptides: first insight into African swine fever virus-derived T cell epitopes presented by swine MHC class I. J Virol. 2022 Feb 23;96(4):e0137821. (IF=5.103)
22. Tao Wang#, Liang Wang#, Yu Han, Li Pan, Jing Yang, Maowen Sun, Pingping Zhou, Yuan Sun*, Yuhai Bi*, Hua-Ji Qiu*. Adaptation of African swine fever virus to HEK293T cells. Transbound Emerg Dis. 2021, 68(5): 2853-2866. (IF=3.293)
23. Li Pan#, Rui Luo#, Tao Wang, Mengnan Qi, Bing Wang, Maowen Sun, Yuzi Luo, Chen Ji, Yuan Sun*, Hua-Ji Qiu*. Efficient inactivation of African swine fever virus by a highly complexed iodine. Vet Microbiol. 2021 Dec;263:109245. (IF=3.293)
24. Teshale Teklue, Tao Wang, Yuzi Luo, Rongliang Hu, Yuan Sun*, Hua-Ji Qiu*. Generation and evaluation of an African swine fever virus mutant with deletion of the CD2v and UK genes. Vaccines (Basel). 2020 Dec 14;8(4):763. (IF=4.50)
25. Wang Y#, Wang S#, Wu H#, Liu X, Ma J, Khan MA, Riaz A, Wang L*, Qiu HJ*, Sun Y*. Compartmentalized neuronal culture for viral transport research. Front Microbiol. 2020; 11:1470. (IF=4.24)
26. Qi H#, Wu H#, Abid M, Qiu HJ*, Sun Y*. Establishment of a fosmid library for pseudorabies virus SC strain and application in viral neuronal tracing. Front Microbiol. 2020; 11:1168. (IF=4.24)
27. Miao Li#, Yi Wang#, Hongyu Cui, Yongfeng Li, Yuan Sun*, Hua-Ji Qiu*. Characterization of lactic acid bacteria isolated from the gastrointestinal tract of a wild boar as potential probiotics. Front Vet Sci. 2020 Feb 11;7:49. (IF=3.41)
28. Abid M, Teklue T, Li Y, Wu H, Wang T, Qiu HJ*, Sun Y*. Generation and immunogenicity of a recombinant Pseudorabies virus co-expressing classical swine fever virus E2 protein and porcine Circovirus type 2 capsid protein based on fosmid library platform. Pathogens, 2019; 8(4). (IF=3.10)
29. Zhou M, Abid M, Yin H, Wu H, Teklue T, Qiu HJ*, Sun Y*. Establishment of an efficient and flexible genetic manipulation platform based on a fosmid library for rapid generation of recombinant pseudorabies virus. Front Microbiol. 2018 Sep 5;9:2132. (IF=4.19)
30. Li LF, Yu J, Zhang Y, Yang Q, Li Y, Zhang L, Wang J, Li S, Luo Y, Sun Y*, Qiu HJ*. 2017. Interferon-inducible oligoadenylate synthetase-like protein acts as an antiviral effector against classical swine fever virus via the MDA5-mediated type I interferon signaling pathway. J Virol. 2017 May 12;91(11). (IF=4.606)
31. Luo Y, Ji S, Lei JL, Xiang GT, Liu Y, Gao Y, Meng XY, Zheng G, Zhang EY, Wang Y, Du ML, Li Y, Li S, He XJ, Sun Y*, Qiu HJ*. 2017. Efficacy evaluation of the C-strain-based vaccines against the subgenotype 2.1d classical swine fever virus emerging in China. Vet Microbiol. 2017 Mar;201:154-161. (IF=2.564)
32. Sun Y, Luo Y, Wang CH, Yuan J, Li N, Song K, Qiu HJ. 2016. Control of swine pseudorabies in China: Opportunities and limitations. Vet Microbiol. 2016 Feb 1;183:119-24. (IF=2.564)
33. Xia SL, Du M, Lei JL, Liu Y, Wang Y, Ji S, Xiang GT, Li LF, Cong X, Luo Y, Shao L, Qiu HJ*, Sun Y*. 2016. Piglets with maternally derived antibodies from sows immunized with rAdV-SFV-E2 were completely protected against lethal CSFV challenge. Vet Microbiol. 2016 Jul 15;190:38-42. (IF=2.564)
34. Xia SL, Lei JL, Du M, Wang Y, Cong X, Xiang GT, Li LF, Yu S, Du E, Liu S, Sun Y*, Qiu HJ*. 2016. Enhanced protective immunity of the chimeric vector-based vaccine rAdV-SFV-E2 against classical swine fever in pigs by a Salmonella bacterial ghost adjuvant. Vet Res. 2016 Jun 14;47(1):64. (IF=2.928)
35. Xia SL, Xiang GT, Lei JL, Du M, Wang Y, Zhou M, Liu Y, Ji S, Wang YL, Luo Y, Sun Y*, Qiu HJ*. 2016. Efficacy of the marker vaccine rAdV-SFV-E2 against classical swine fever in the presence of maternally derived antibodies to rAdV-SFV-E2 or C-strain. Vet Microbiol. 2016 Nov 30;196:50-54. (IF=2.564)
36. Lei JL, Xia SL, Wang Y, Du M, Xiang GT, Cong X, Luo Y, Li LF, Zhang L, Yu J, Hu Y, Qiu HJ*, Sun Y*. 2016. Safety and immunogenicity of a gE/gI/TK gene-deleted pseudorabies virus variant expressing the E2 protein of classical swine fever virus in pigs. Immunol Lett. 2016 Jun;174:63-71. (IF=2.483)
37. Cong X, Lei JL, Xia SL, Wang YM, Li Y, Li S, Luo Y, Sun Y*, Qiu HJ*. 2016. Pathogenicity and immunogenicity of a gE/gI/TK gene-deleted pseudorabies virus variant in susceptible animals. Vet Microbiol. 2016 Jan 15;182:170-7. (IF=2.564)
38. Wang Y, Xia SL, Lei JL, Cong X, Xiang GT, Luo Y, Sun Y*, Qiu HJ*. 2015. Dose-dependent pathogenicity of a pseudorabies virus variant in pigs inoculated via intranasal route. Veterinary immunology and immunopathology 168:147-152. (IF=1.664)
39. Wang Y, Yuan J, Cong X, Qin HY, Wang CH, Li Y, Li S, Luo Y, Sun Y*, Qiu HJ*. 2015. Generation and efficacy evaluation of a recombinant pseudorabies virus variant expressing the e2 protein of classical swine fever virus in pigs. Clinical and vaccine immunology: CVI. 22:1121-1129. (IF=2.277)
40. Luo Y, Li L, Austermann-Busch S, Dong M, Xu J, Shao L, Lei J, Li N, He WR, Zhao B, Li S, Li Y, Liu L, Becher P, Sun Y*, Qiu HJ*. 2015. Enhanced expression of the Erns protein of classical swine fever virus in yeast and its application in an indirect enzyme-linked immunosorbent assay for antibody differentiation of infected from vaccinated animals. Journal of virological methods 222:22-27. (IF=1.508)
41. Luo Y, Li N, Cong X, Wang CH, Du M, Li L, Zhao B, Yuan J, Liu DD, Li S, Li Y, Sun Y*, Qiu HJ*. 2014. Pathogenicity and genomic characterization of a pseudorabies virus variant isolated from Bartha-K61-vaccinated swine population in China. Vet Microbiol 174:107-115. (IF=2.564)
42. Wang CH, Yuan J, Qin HY, Luo Y, Cong X, Li Y, Chen J, Li S, Sun Y*, Qiu HJ*. 2014. A novel gE-deleted pseudorabies virus (PRV) provides rapid and complete protection from lethal challenge with the PRV variant emerging in Bartha-K61-vaccinated swine population in China. Vaccine. 2014 Jun 5;32(27):3379-85. (IF=3.413)
43. Sun Y, Tian DY, Li S, Meng QL, Zhao BB, Li Y, Li D, Ling LJ, Liao YJ, Qiu HJ. 2013. Comprehensive evaluation of the adenovirus/alphavirus-replicon chimeric vector-based vaccine rAdV-SFV-E2 against classical swine fever. Vaccine 31:538-544. (IF=3.413)
44. Tian DY#, Sun Y#, Wai SF, Lee FK, Meng QL, Suen KM, Wang N, Han W, Li S, Li YF, Li D, Ling LJ, Liao YJ, Qiu HJ. 2012. Enhancement of the immunogenicity of an alphavirus replicon-based DNA vaccine against classical swine fever by electroporation and coinjection with a plasmid expressing porcine interleukin 2. Vaccine 30:3587-3594. (IF=3.413)
45. Sun Y, Jiang Q, Tian DY, Lin H, Li H, Han QY, Han W, Si CD, Hu SP, Zhang Z, Qu LD, Qiu HJ. 2011. Experimental infection of Bama miniature pigs with a highly virulent classical swine fever virus. Virology journal 8:452. (IF=2.362)
46. Sun Y, Li HY, Tian DY, Han QY, Zhang X, Li N, Qiu HJ. 2011. A novel alphavirus replicon-vectored vaccine delivered by adenovirus induces sterile immunity against classical swine fever. Vaccine 29:8364-8372. (IF=3.413)
47. Sun Y, Li HY, Zhang XJ, Chang TM, He F, Wang XP, Liu DF, Qiu HJ. 2011. Comparison of the protective efficacy of recombinant adenoviruses against classical swine fever. Immunology letters 135:43-49. (IF=2.483)
48. Sun Y, Li N, Li HY, Li M, Qiu HJ. 2010. Enhanced immunity against classical swine fever in pigs induced by prime-boost immunization using an alphavirus replicon-vectored DNA vaccine and a recombinant adenovirus. Veterinary immunology and immunopathology 137:20-27. (IF=1.664)
六、專利
1. 仇華吉;孫元;雷建林;羅玉子. 表達(dá)豬瘟病毒E2蛋白的重組偽狂犬病病毒變異株及構(gòu)建方法和應(yīng)用. ZL201610236150.1 專利申請日:2016年4月15日 授權(quán)公告日:2020年8月18日
2. 仇華吉;孫元;羅玉子;李素;李永鋒. 表達(dá)豬瘟病毒E2蛋白的重組偽狂犬病病毒變異株及其應(yīng)用. ZL201510296045.2 專利申請日:2015年6月2日 授權(quán)公告日:2018年8月31日
3. 仇華吉;孫元;羅玉子;李素;李永鋒. 偽狂犬病病毒變異株雙基因缺失毒株及其構(gòu)建方法和應(yīng)用. ZL201410105058.2 專利申請日:2014年3月20日 授權(quán)公告日:2017年1月25日
4. 仇華吉;孫元. 適應(yīng)無血清培養(yǎng)的HEK293細(xì)胞系及其應(yīng)用. ZL201210071586.1 專利申請日:2012年3月19日 授權(quán)公告日:2013年5月8日
5. 仇華吉;孫元;李娜;李宏宇. 腺病毒/甲病毒復(fù)制子嵌合載體豬瘟疫苗及其應(yīng)用. ZL201010297576.0 專利申請日:2010年9月30日 授權(quán)公告日:2012年6月27日
6. 仇華吉;周末;孫元. 偽狂犬病病毒基因組Fosmid文庫、構(gòu)建方法及其在構(gòu)建突變體中的應(yīng)用. ZL201810374527.9 專利申請日:2018年4月24日 授權(quán)公告日:2022年3月18日
7. 仇華吉;羅玉子;孫元;孟星宇;李素;李永鋒. 豬瘟病毒截短E2蛋白及其應(yīng)用. ZL201711119596.7 專利申請日:2017年11月14日 授權(quán)公告日:2020年7月24日
8. 仇華吉;羅玉子;孫元;孟星宇;李素;李永鋒. 檢測非洲豬瘟病毒的PCR引物、試劑盒及其應(yīng)用. ZL201610183350.5 專利申請日:2016年3月28日 授權(quán)公告日:2019年5月14日
9. 仇華吉;李彥偉;孫元;王克雄;王牟平;趙飛;趙憲成. 重組腺病毒疫苗株高適應(yīng)性HEK293克隆細(xì)胞株及其應(yīng)用. ZL201510570856.7 專利申請日:2015年9月9日 授權(quán)公告日:2018年6月26日
10. 仇華吉;李永鋒;孫元;李素;羅玉子. 綠色熒光蛋白標(biāo)記的重組豬瘟病毒及其拯救方法和應(yīng)用. ZL201310069486.X 專利申請日:2013年3月5日 授權(quán)公告日:2015年2月11日
11. 仇華吉;張興娟;孫元;劉大飛. 用于可視化檢測豬瘟病毒野毒株的RT-LAMP引物. ZL200910180317.7 專利申請日:2009年10月22日 授權(quán)公告日:2012年4月18日
七、轉(zhuǎn)基因安全證書和臨床試驗(yàn)批件
1. 表達(dá)豬瘟病毒E2基因和偽狂犬病病毒UL49基因的重組腺病毒活載體疫苗rAdV-E2-UL49的安全證書. 農(nóng)基安證字(2010)第063號
2. 表達(dá)豬瘟病毒E2基因的腺病毒/甲病毒復(fù)制子嵌合疫苗rAdV-SFV-E2的安全證書. 農(nóng)基安證字(2013)第273號
3. 豬瘟基因工程活疫苗(rAdV-SFV-E2株)臨床試驗(yàn)批件. 批件號:2017065
八、學(xué)術(shù)組織
1. 中國畜牧獸醫(yī)學(xué)會動(dòng)物傳染病學(xué)分會青年學(xué)者專業(yè)組副主任委員. 2019年8月至2023年8月
2. 黑龍江省畜牧獸醫(yī)學(xué)會動(dòng)物傳染病學(xué)分會第九屆理事會副秘書長. 2020年11月至2024年11月
3. 野生動(dòng)物生物安全管控國家創(chuàng)新聯(lián)盟常務(wù)理事. 2021年11月至2024年11月
4. 中國畜牧獸醫(yī)學(xué)會生物技術(shù)學(xué)分會第六屆理事會理事. 2020年10月至2024年10月
5. 東北養(yǎng)豬研究會第十二屆理事會理事. 2016年7月至2020年7月
九、學(xué)術(shù)榮譽(yù)
1. 中國農(nóng)業(yè)科學(xué)院—大北農(nóng)人才獎(jiǎng)優(yōu)秀青年人才獎(jiǎng),中國農(nóng)業(yè)科學(xué)院. 2023年1月
2. 龍江學(xué)者支持計(jì)劃,青年學(xué)者,黑龍江省教育廳,編號Q201907. 2019年11月
3. 豬瘟基因工程活疫苗(rAdV-SFV-E2株)的創(chuàng)制,大北農(nóng)科技獎(jiǎng). 2019-12-31(排名第2)
4. 省部級獎(jiǎng)勵(lì),黑龍江省科技進(jìn)步二等獎(jiǎng),黑龍江省人民政府. 2019-10-31(排名第5)
5. 省部級獎(jiǎng)勵(lì),中國農(nóng)業(yè)科學(xué)院杰出科技創(chuàng)新獎(jiǎng),中國農(nóng)業(yè)科學(xué). 2018-08-27(排名第5)
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