1、個人簡歷
劉永振，男，博士，研究員，博士生導(dǎo)師。禽免疫抑制病研究團隊骨干專家，中國農(nóng)業(yè)科學(xué)院“青年英才”引進工程所級入選者。長期從事動物病毒學(xué)和細(xì)胞生物學(xué)相關(guān)領(lǐng)域的基礎(chǔ)與應(yīng)用基礎(chǔ)研究，尤其是在禽皰疹病毒逃避宿主天然免疫反應(yīng)機制、誘導(dǎo)宿主細(xì)胞代謝重塑等方面有較為突出的科研成果。在PNAS、mBio、PLoS Pathogens、JVI等學(xué)術(shù)期刊發(fā)表20余篇研究論文。其中以第一作者（含共同）在mBio、Plos Pathogens、JVI 等學(xué)術(shù)期刊發(fā)表SCI論文7篇。
2、聯(lián)系方式
研究方向：獸醫(yī)微生物及其分子生物學(xué)
電話：0451-51051692
電子郵箱：liuyongzhen@caas.cn
通訊地址：黑龍江省哈爾濱市香坊區(qū)哈平路678號
3、教育經(jīng)歷
2009.09-2013.06 青島農(nóng)業(yè)大學(xué)，動物醫(yī)學(xué)專業(yè)，學(xué)士
2013.09-2019.07 中國農(nóng)業(yè)科學(xué)院哈爾濱獸醫(yī)研究所，預(yù)防獸醫(yī)學(xué)，博士
4、工作經(jīng)歷
2019.08-2023.06 美國南加州大學(xué)，博士后
2023.07-今 中國農(nóng)業(yè)科學(xué)院哈爾濱獸醫(yī)研究所，研究員
5、承擔(dān)主要項目
1．農(nóng)業(yè)生物育種重大項目子課題, 雞馬立克氏病病毒致病過程的分子機理研究（2023ZD0405303），2023.09-2025.12 ，100 萬元，主持
2．黑龍江省留學(xué)回國人員擇優(yōu)資助（啟動類），單細(xì)胞精度解析雞胸腺發(fā)育的細(xì)胞圖譜及雞T細(xì)胞全譜系的形成，2023.11-2025.12，5 萬元，主持
6、代表性論文
1. Liu Y#, Qin C, Rao Y, Ngo C, Feng JJ, Zhao J, Zhang S, Wang TY, Carriere J, Savas AC, Zarinfar M, Rice S, Yang H, Yuan W, Camarero JA, Yu J, Chen XS, Zhang C, Feng P. SARS-CoV-2 Nsp5 Demonstrates Two Distinct Mechanisms Targeting RIG-I and MAVS To Evade the Innate Immune Response. mBio. 2021, 12(5): e0233521.
2. Li K#, Liu Y#, Xu Z, Zhang Y, Luo D, Gao Y, Qian Y, Bao C, Liu C, Zhang Y, Qi X, Cui H, Wang Y, Gao L, Wang X. Avian oncogenic herpesvirus antagonizes the cGAS-STING DNAsensing pathway to mediate immune evasion. PLoS Pathog. 2019, 15(9): e1007999.
3. Liu Y#, Gao L#, Xu Z, Luo D, Zhang Y, Gao Y, Liu C, Zhang Y, Qi X, Cui H, Li K, Wang X. Marek's Disease Virus RLORF4 Inhibits Type I Interferon Production by Antagonizing NFkappaB Activation. J Virol. 2019, 93(18): e01037-19.
4. Liu Y#, Xu Z# , Zhang Y, Yu M, Wang S, Gao Y, Liu C, Zhang Y, Gao L, Qi X, Cui H, Pan Q, Li K, Wang X. Marek's disease virus as a CRISPR/Cas9 delivery system to defend against avian leukosis virus infection in chickens. Vet Microbiol. 2020, 242:108589.
5. Li K#, Liu Y#, Xu Z, Zhang Y, Yao Y, Nair V, Liu C, Zhang Y, Gao Y, Qi X, Cui H, Gao L, Wang X. Prevention of Avian Retrovirus Infection in Chickens Using CRISPR-Cas9 Delivered by Marek's Disease Virus. Mol Ther Nucleic Acids. 2020, 21:343-353.
6. Liu Y#, Li K#, Cui H, Gao L, Liu C, Zhang Y, Gao Y, and Wang X. Comparison of different sites in recombinant Marek's disease virus for the expression of green fluorescent protein. Virus Res. 2017 May 2;235:82-85
7. Liu Y#, Li K#, Gao Y, Gao L, Zhong L, Zhang Y, Liu C, Zhang Y, and Wang X. Recombinant Marek's Disease Virus as a Vector Based Vaccine against Avian Leukosis Virus Subgroup J in Chicken. Viruses. 2016, 8(11):301.
8. Qin C, Rao Y, Yuan H, Wang TY, Zhao J, Espinosa B, Liu Y, Zhang S, Savas AC, Liu Q, Zarinfar M, Rice S, Henley J, Comai L, Graham NA, Chen C, Zhang C, Feng P. SARS-CoV-2 couples evasion of inflammatory response to activated nucleotide synthesis. Proc Natl Acad Sci U S A. 2022 Jun 28;119(26): e2122897119.
9. Yun B, Zhang Y, Liu Y, Guan X, Wang Y, Qi X, Cui H, Liu C, Zhang Y, Gao H, Gao L, Li K, Gao Y, Wang X. TMPRSS12 Is an Activating Protease for Subtype B Avian Metapneumovirus. J Virol. 2016 Nov 28;90(24):11231-11246.
10. Gao L, Li K, Zhang Y, Liu Y, Liu C, Zhang Y, Gao Y, Qi X, Cui H, Wang Y, Wang X. Inhibition of DNA-Sensing Pathway by Marek's Disease Virus VP23 Protein through Suppression of Interferon Regulatory Factor 7 Activation. J Virol. 2019 Feb 5;93(4): e01934-18.
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